Allison Jevitt
Visiting Assistant Professor
Education
Ph.D. - Florida State University
B.S. - Florida State University
Research Interest
At the core of my research program is an ongoing investigation into the mechanisms by which cells control their nuclear morphology and chromatin structure, specifically to understand the consequences of abnormal regulation in these processes in cancer. To address these questions both in vivo and in vitro, I have used several model systems, including the fruit fly (Drosophila melanogaster), the African clawed frog (Xenopus laevis), and human cell cultures. My research employs a diverse array of techniques in molecular biology and genetics, as well as cell culture, microinjection, dissection, immunohistochemistry, microscopy, DNA/RNA sequencing, and bioinformatics analysis.
Courses Taught
BIOL 312L: Molecular Biology Lab
BIOL 305L: Genetics Lab
Selected Publications
Jevitt, A.M., Rankin, B.D., Chen, J. and Rankin, S., 2023. The cohesin modifier ESCO2 is stable during DNA replication. Chromosome Research, 31(1), p.6.
Roe, M.M., Do, T., Turner, S., Jevitt, A.M., Chlebicz, M., White, K., Oomens, A.G., Rankin, S., Kovats, S. and Gappa-Fahlenkamp, H., 2023. Blood myeloid cells differentiate to lung resident cells and respond to pathogen stimuli in a 3D human tissue-engineered lung model. Frontiers in Bioengineering and Biotechnology, 11, p.1212230.
Jevitt, A.M. and Rankin, S., 2022. The study of cell division control and DNA replication in Xenopus egg extracts. In Xenopus (pp. 13-24). CRC Press.
Chatterjee, D., Costa, C.A.M., Wang, X.F., Jevitt, A., Huang, Y.C. and Deng, W.M., 2022. Single-cell transcriptomics identifies Keap1-Nrf2 regulated collective invasion in a Drosophila tumor model. Elife, 11, p.e80956.
Jia, D., Jevitt, A., Huang, Y.C., Ramos, B. and Deng, W.M., 2022. Developmental regulation of epithelial cell cuboidal-to-squamous transition in Drosophila follicle cells. Developmental biology, 491, pp.113-125.
Jevitt, A., Huang, Y.C., Zhang, S.M., Chatterjee, D., Wang, X.F., Xie, G.Q. and Deng, W.M., 2021. Modeling notch-induced tumor cell survival in the Drosophila ovary identifies cellular and transcriptional response to nuclear NICD accumulation. Cells, 10(9), p.2222.
Jevitt, A., Chatterjee, D., Xie, G., Wang, X.F., Otwell, T., Huang, Y.C. and Deng, W.M., 2020. A single-cell atlas of adult Drosophila ovary identifies transcriptional programs and somatic cell lineage regulating oogenesis. PLOS biology, 18(4), p.e3000538.